null

SMILES: O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cccc2C(=O)c3ccccc3-c12

InChI Key: InChIKey=INMSGESUKZJUQI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 36417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D1 (Homo sapiens (Human))	BDBM36417 (9-Oxo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidaz...) Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cccc2C(=O)c3ccccc3-c12 Show InChI InChI=1S/C28H26N4O3/c33-26-20-7-2-1-6-19(20)25-21(26)8-5-9-22(25)27(34)29-14-17-31-15-12-18(13-16-31)32-24-11-4-3-10-23(24)30-28(32)35/h1-11,18H,12-17H2,(H,29,34)(H,30,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D1(PLD1).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36417 (9-Oxo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidaz...) Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cccc2C(=O)c3ccccc3-c12 Show InChI InChI=1S/C28H26N4O3/c33-26-20-7-2-1-6-19(20)25-21(26)8-5-9-22(25)27(34)29-14-17-31-15-12-18(13-16-31)32-24-11-4-3-10-23(24)30-28(32)35/h1-11,18H,12-17H2,(H,29,34)(H,30,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D2(PLD2).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36417 (9-Oxo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidaz...) Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cccc2C(=O)c3ccccc3-c12 Show InChI InChI=1S/C28H26N4O3/c33-26-20-7-2-1-6-19(20)25-21(26)8-5-9-22(25)27(34)29-14-17-31-15-12-18(13-16-31)32-24-11-4-3-10-23(24)30-28(32)35/h1-11,18H,12-17H2,(H,29,34)(H,30,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using HEK293-gfpPLD2 cell line				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36417 (9-Oxo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidaz...) Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cccc2C(=O)c3ccccc3-c12 Show InChI InChI=1S/C28H26N4O3/c33-26-20-7-2-1-6-19(20)25-21(26)8-5-9-22(25)27(34)29-14-17-31-15-12-18(13-16-31)32-24-11-4-3-10-23(24)30-28(32)35/h1-11,18H,12-17H2,(H,29,34)(H,30,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using human non-small-cell lung cancer cell line, Calu-1				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36417 (9-Oxo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidaz...) Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cccc2C(=O)c3ccccc3-c12 Show InChI InChI=1S/C28H26N4O3/c33-26-20-7-2-1-6-19(20)25-21(26)8-5-9-22(25)27(34)29-14-17-31-15-12-18(13-16-31)32-24-11-4-3-10-23(24)30-28(32)35/h1-11,18H,12-17H2,(H,29,34)(H,30,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair