BDBM3642 2-[({4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]quinazolin-6-yl}methyl)(methyl)amino]acetic acid::5-[(3-bromophenyl)amino]-3-[[N-(carboxymethyl)-N-methylamino]methyl]pyrrolo[3,2-g]quinazoline hydrochloride::Pyrroloquinazoline deriv. 9

SMILES: CN(CC(O)=O)Cc1c[nH]c2cc3ncnc(Nc4cccc(Br)c4)c3cc12

InChI Key: InChIKey=DBSQOKFNDAENBI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3642 (2-[({4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]qui...) Show SMILES CN(CC(O)=O)Cc1c[nH]c2cc3ncnc(Nc4cccc(Br)c4)c3cc12 Show InChI InChI=1S/C20H18BrN5O2/c1-26(10-19(27)28)9-12-8-22-17-7-18-16(6-15(12)17)20(24-11-23-18)25-14-4-2-3-13(21)5-14/h2-8,11,22H,9-10H2,1H3,(H,27,28)(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	589	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISA				Eur J Med Chem 43: 781-91 (2008) Article DOI: 10.1016/j.ejmech.2007.06.006 BindingDB Entry DOI: 10.7270/Q2DJ5GXN
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3642 (2-[({4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]qui...) Show SMILES CN(CC(O)=O)Cc1c[nH]c2cc3ncnc(Nc4cccc(Br)c4)c3cc12 Show InChI InChI=1S/C20H18BrN5O2/c1-26(10-19(27)28)9-12-8-22-17-7-18-16(6-15(12)17)20(24-11-23-18)25-14-4-2-3-13(21)5-14/h2-8,11,22H,9-10H2,1H3,(H,27,28)(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.720	n/a	n/a	n/a	n/a	7.4	25
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 1519-29 (1997) Article DOI: 10.1021/jm960789h BindingDB Entry DOI: 10.7270/Q2SJ1HRQ
					More data for this Ligand-Target Pair