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SMILES: FC(F)(F)Cn1c2cc(ncc2c2[nH]ncc2c1=O)-c1ccccc1CN1CCOCC1

InChI Key: InChIKey=FTLRZSBEQHQLTG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364232   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))		BDBM364232
PNG
(US9856257, 17)
Show SMILES FC(F)(F)Cn1c2cc(ncc2c2[nH]ncc2c1=O)-c1ccccc1CN1CCOCC1
Show InChI InChI=1S/C22H20F3N5O2/c23-22(24,25)13-30-19-9-18(26-10-16(19)20-17(21(30)31)11-27-28-20)15-4-2-1-3-14(15)12-29-5-7-32-8-6-29/h1-4,9-11H,5-8,12-13H2,(H,27,28)
PDB
MMDB

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n/an/a 75n/an/an/an/an/an/a



Wyeth Research



Assay Description
For the enzymatic test, human MetAP2 protein was obtained from a culture supernatant of insect cells (sf9) infected with MetAP2 recombinant baculovir...

Bioorg Med Chem 15: 3321-33 (2007)


BindingDB Entry DOI: 10.7270/Q26T0PZK
More data for this
Ligand-Target Pair