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SMILES: Fc1ncccc1-c1cc2n(CC(F)(F)F)c(=O)c3cn[nH]c3c2cn1

InChI Key: InChIKey=JRENAWNEJQGVOH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364251   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))		BDBM364251
PNG
(US9856257, 36)
Show SMILES Fc1ncccc1-c1cc2n(CC(F)(F)F)c(=O)c3cn[nH]c3c2cn1
Show InChI InChI=1S/C16H9F4N5O/c17-14-8(2-1-3-21-14)11-4-12-9(5-22-11)13-10(6-23-24-13)15(26)25(12)7-16(18,19)20/h1-6H,7H2,(H,23,24)
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MMDB

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n/an/a 31n/an/an/an/an/an/a



Wyeth Research



Assay Description
For the enzymatic test, human MetAP2 protein was obtained from a culture supernatant of insect cells (sf9) infected with MetAP2 recombinant baculovir...

Bioorg Med Chem 15: 3321-33 (2007)


BindingDB Entry DOI: 10.7270/Q26T0PZK
More data for this
Ligand-Target Pair