BDBM36428 3,4,5-Trimethoxy-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide, 55::CID25105703

SMILES: COc1cc(cc(OC)c1OC)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O

InChI Key: InChIKey=WNYCYGCNORZQPH-UHFFFAOYSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 36428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36428 (3,4,5-Trimethoxy-N-(2-(4-(2-oxo-2,3-dihydro-1H-ben...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H30N4O5/c1-31-20-14-16(15-21(32-2)22(20)33-3)23(29)25-10-13-27-11-8-17(9-12-27)28-19-7-5-4-6-18(19)26-24(28)30/h4-7,14-15,17H,8-13H2,1-3H3,(H,25,29)(H,26,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D1(PLD1).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36428 (3,4,5-Trimethoxy-N-(2-(4-(2-oxo-2,3-dihydro-1H-ben...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H30N4O5/c1-31-20-14-16(15-21(32-2)22(20)33-3)23(29)25-10-13-27-11-8-17(9-12-27)28-19-7-5-4-6-18(19)26-24(28)30/h4-7,14-15,17H,8-13H2,1-3H3,(H,25,29)(H,26,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D2(PLD2).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36428 (3,4,5-Trimethoxy-N-(2-(4-(2-oxo-2,3-dihydro-1H-ben...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H30N4O5/c1-31-20-14-16(15-21(32-2)22(20)33-3)23(29)25-10-13-27-11-8-17(9-12-27)28-19-7-5-4-6-18(19)26-24(28)30/h4-7,14-15,17H,8-13H2,1-3H3,(H,25,29)(H,26,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	79	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using HEK293-gfpPLD2 cell line				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36428 (3,4,5-Trimethoxy-N-(2-(4-(2-oxo-2,3-dihydro-1H-ben...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H30N4O5/c1-31-20-14-16(15-21(32-2)22(20)33-3)23(29)25-10-13-27-11-8-17(9-12-27)28-19-7-5-4-6-18(19)26-24(28)30/h4-7,14-15,17H,8-13H2,1-3H3,(H,25,29)(H,26,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using human non-small-cell lung cancer cell line, Calu-1				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36428 (3,4,5-Trimethoxy-N-(2-(4-(2-oxo-2,3-dihydro-1H-ben...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H30N4O5/c1-31-20-14-16(15-21(32-2)22(20)33-3)23(29)25-10-13-27-11-8-17(9-12-27)28-19-7-5-4-6-18(19)26-24(28)30/h4-7,14-15,17H,8-13H2,1-3H3,(H,25,29)(H,26,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair