BDBM36452 6-[[(3-Carboxy-benzylidene)-aminooxy]ethoxyimino]methyl]uracil, 14::CID25210531

SMILES: OC(=O)c1cccc(\C=N\OCCO\N=C\c2cc(=O)[nH]c(=O)[nH]2)c1

InChI Key: InChIKey=TUYDQQMKXSQIQG-GONBZBRSSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 36452   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (UNG) (Homo sapiens (Human))	BDBM36452 (6-[[(3-Carboxy-benzylidene)-aminooxy]ethoxyimino]m...) Show SMILES OC(=O)c1cccc(\C=N\OCCO\N=C\c2cc(=O)[nH]c(=O)[nH]2)c1 Show InChI InChI=1S/C15H14N4O6/c20-13-7-12(18-15(23)19-13)9-17-25-5-4-24-16-8-10-2-1-3-11(6-10)14(21)22/h1-3,6-9H,4-5H2,(H,21,22)(H2,18,19,20,23)/b16-8+,17-9+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem	DrugBank MMDB PDB Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	8.0	n/a
Johns Hopkins University					Assay Description Inhibition of human uracil DNA glycosylase using high-throughput fluorescent molecular beacon DNA substrate.				Nat Chem Biol 5: 407-13 (2009) Article DOI: 10.1038/nchembio.163 BindingDB Entry DOI: 10.7270/Q2W37TP8
					More data for this Ligand-Target Pair				3D Structure (crystal)