BDBM36484 (S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxohexan-2-yl)carbamate, 21::CID10435243
SMILES: CC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
InChI Key: InChIKey=QPYCOBUGIVWEDU-QFIPXVFZSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM36484 ((S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 643 | n/a | n/a | n/a | n/a | 7.4 | 0 |
Dana-Farber Cancer Institute | Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add... | Nat Chem Biol 6: 238-243 (2010) Article DOI: 10.1038/nchembio.313 BindingDB Entry DOI: 10.7270/Q2C53J66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 9 (Homo sapiens (Human)) | BDBM36484 ((S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | 7.4 | 0 |
Dana-Farber Cancer Institute | Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add... | Nat Chem Biol 6: 238-243 (2010) Article DOI: 10.1038/nchembio.313 BindingDB Entry DOI: 10.7270/Q2C53J66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 7 (Homo sapiens (Human)) | BDBM36484 ((S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 786 | n/a | n/a | n/a | n/a | 7.4 | 0 |
Dana-Farber Cancer Institute | Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add... | Nat Chem Biol 6: 238-243 (2010) Article DOI: 10.1038/nchembio.313 BindingDB Entry DOI: 10.7270/Q2C53J66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 5 (Homo sapiens (Human)) | BDBM36484 ((S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chro...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | 7.4 | 0 |
Dana-Farber Cancer Institute | Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add... | Nat Chem Biol 6: 238-243 (2010) Article DOI: 10.1038/nchembio.313 BindingDB Entry DOI: 10.7270/Q2C53J66 | |||||||||||
More data for this Ligand-Target Pair |