BDBM3651 2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}(2-hydroxyethyl)amino)ethan-1-ol::4-[(3-Bromophenyl)amino]-7-[N,N-bis(2-hydroxyethyl)amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3i

SMILES: OCCN(CCO)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1

InChI Key: InChIKey=LYENTQSFLVZYRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3651 (2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin...) Show SMILES OCCN(CCO)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1 Show InChI InChI=1S/C17H18BrN5O2/c18-12-2-1-3-13(8-12)22-17-14-10-19-16(9-15(14)20-11-21-17)23(4-6-24)5-7-25/h1-3,8-11,24-25H,4-7H2,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	25
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 3915-25 (1997) Article DOI: 10.1021/jm970366v BindingDB Entry DOI: 10.7270/Q2NS0S2V
					More data for this Ligand-Target Pair