BDBM3660 4-N-(3-bromophenyl)-7-N-[3-(morpholin-4-yl)propyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-[[3-(4-morpholino)propyl]amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3r

SMILES: Brc1cccc(Nc2ncnc3cc(NCCCN4CCOCC4)ncc23)c1

InChI Key: InChIKey=WPUBKZIJROOKPL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3660 (4-N-(3-bromophenyl)-7-N-[3-(morpholin-4-yl)propyl]...) Show SMILES Brc1cccc(Nc2ncnc3cc(NCCCN4CCOCC4)ncc23)c1 Show InChI InChI=1S/C20H23BrN6O/c21-15-3-1-4-16(11-15)26-20-17-13-23-19(12-18(17)24-14-25-20)22-5-2-6-27-7-9-28-10-8-27/h1,3-4,11-14H,2,5-10H2,(H,22,23)(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.4	25
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 3915-25 (1997) Article DOI: 10.1021/jm970366v BindingDB Entry DOI: 10.7270/Q2NS0S2V
					More data for this Ligand-Target Pair