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SMILES: COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CNCC(O)CN(C)C

InChI Key: InChIKey=TWZSQHIJRXGXTC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 366006   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death 1 ligand 1


(Homo sapiens (Human))		BDBM366006
PNG
(({2,6-dimethoxy-4-[(2-methyl-3- phenylphenyl)metho...)
Show SMILES COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CNCC(O)CN(C)C
Show InChI InChI=1S/C28H36N2O4/c1-20-22(12-9-13-25(20)21-10-7-6-8-11-21)19-34-24-14-27(32-4)26(28(15-24)33-5)17-29-16-23(31)18-30(2)3/h6-15,23,29,31H,16-19H2,1-5H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 53n/an/an/an/an/an/a



Novartis Pharmaceuticals



Assay Description
All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...

J Med Chem 51: 4-16 (2008)


BindingDB Entry DOI: 10.7270/Q2RN3B42
More data for this
Ligand-Target Pair