BDBM3661 4-N-(3-bromophenyl)-7-N-[4-(morpholin-4-yl)butyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Bromophenyl)amino]-7-[[4-(4-morpholino)butyl]-amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3s

SMILES: Brc1cccc(Nc2ncnc3cc(NCCCCN4CCOCC4)ncc23)c1

InChI Key: InChIKey=LGQGASCJEHGWJL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3661 (4-N-(3-bromophenyl)-7-N-[4-(morpholin-4-yl)butyl]p...) Show SMILES Brc1cccc(Nc2ncnc3cc(NCCCCN4CCOCC4)ncc23)c1 Show InChI InChI=1S/C21H25BrN6O/c22-16-4-3-5-17(12-16)27-21-18-14-24-20(13-19(18)25-15-26-21)23-6-1-2-7-28-8-10-29-11-9-28/h3-5,12-15H,1-2,6-11H2,(H,23,24)(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 3915-25 (1997) Article DOI: 10.1021/jm970366v BindingDB Entry DOI: 10.7270/Q2NS0S2V
					More data for this Ligand-Target Pair