BDBM3664 2-{[2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)ethyl](2-hydroxyethyl)amino}ethan-1-ol::4-[(3-Bromophenyl)amino]-7-[[2-[N,N-bis(2-hydroxyethyl)amino]ethyl]amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3v

SMILES: OCCN(CCO)CCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1

InChI Key: InChIKey=NOLLIFGERWLBPP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3664   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3664 (2-{[2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrim...) Show SMILES OCCN(CCO)CCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1 Show InChI InChI=1S/C19H23BrN6O2/c20-14-2-1-3-15(10-14)25-19-16-12-22-18(11-17(16)23-13-24-19)21-4-5-26(6-8-27)7-9-28/h1-3,10-13,27-28H,4-9H2,(H,21,22)(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 3915-25 (1997) Article DOI: 10.1021/jm970366v BindingDB Entry DOI: 10.7270/Q2NS0S2V
					More data for this Ligand-Target Pair