BDBM3672 2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}(methyl)amino)acetic acid::4-[(3-Bromophenyl)amino]-7-[N-(carboxymethyl)-N-methylamino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3dd

SMILES: CN(CC(O)=O)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1

InChI Key: InChIKey=GYZRHMIPWQOSOA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3672 (2-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin...) Show SMILES CN(CC(O)=O)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1 Show InChI InChI=1S/C16H14BrN5O2/c1-22(8-15(23)24)14-6-13-12(7-18-14)16(20-9-19-13)21-11-4-2-3-10(17)5-11/h2-7,9H,8H2,1H3,(H,23,24)(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 3915-25 (1997) Article DOI: 10.1021/jm970366v BindingDB Entry DOI: 10.7270/Q2NS0S2V
					More data for this Ligand-Target Pair