BDBM3675 7-N-[4-(dimethylamino)butyl]-4-N-(3-methylphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::7-[[4-(Dimethylamino)butyl]amino]-4-[(3-methylphenyl)amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 4n

SMILES: CN(C)CCCCNc1cc2ncnc(Nc3cccc(C)c3)c2cn1

InChI Key: InChIKey=ANAQVLGHFOBDLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3675 (7-N-[4-(dimethylamino)butyl]-4-N-(3-methylphenyl)p...) Show SMILES CN(C)CCCCNc1cc2ncnc(Nc3cccc(C)c3)c2cn1 Show InChI InChI=1S/C20H26N6/c1-15-7-6-8-16(11-15)25-20-17-13-22-19(12-18(17)23-14-24-20)21-9-4-5-10-26(2)3/h6-8,11-14H,4-5,9-10H2,1-3H3,(H,21,22)(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 3915-25 (1997) Article DOI: 10.1021/jm970366v BindingDB Entry DOI: 10.7270/Q2NS0S2V
					More data for this Ligand-Target Pair