BDBM367619 N-((1R,2R)-1-(4-cyclopropoxyphenyl)- 1-hydroxy-3-(pyrrolidin-1-yl)propan-2- yl)-7-(4-fluorophenyl)-1H- benzo[d][1,2]oxazine-4-carboxamide::US10227312, Example 4::US10759769, Example 4

SMILES: O[C@@H]([C@@H](CN1CCCC1)NC(=O)C1=NOCc2cc(ccc12)-c1ccc(F)cc1)c1ccc(OC2CC2)cc1

InChI Key: InChIKey=LLQSWVCYMQGIFA-PQHLKRTFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367619   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ceramide glucosyltransferase (Homo sapiens (Human))	BDBM367619 (N-((1R,2R)-1-(4-cyclopropoxyphenyl)- 1-hydroxy-3-(...) Show SMILES O[C@@H]([C@@H](CN1CCCC1)NC(=O)C1=NOCc2cc(ccc12)-c1ccc(F)cc1)c1ccc(OC2CC2)cc1 |r,t:13| Show InChI InChI=1S/C31H32FN3O4/c32-24-8-3-20(4-9-24)22-7-14-27-23(17-22)19-38-34-29(27)31(37)33-28(18-35-15-1-2-16-35)30(36)21-5-10-25(11-6-21)39-26-12-13-26/h3-11,14,17,26,28,30,36H,1-2,12-13,15-16,18-19H2,(H,33,37)/t28-,30-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Protein concentration was determined using BCA assay kit. Sixty micrograms of MDCK cell lysate was incubated with various concentrations of a compoun...				US Patent US10759769 (2020)
					More data for this Ligand-Target Pair
Ceramide glucosyltransferase (Homo sapiens (Human))	BDBM367619 (N-((1R,2R)-1-(4-cyclopropoxyphenyl)- 1-hydroxy-3-(...) Show SMILES O[C@@H]([C@@H](CN1CCCC1)NC(=O)C1=NOCc2cc(ccc12)-c1ccc(F)cc1)c1ccc(OC2CC2)cc1 |r,t:13| Show InChI InChI=1S/C31H32FN3O4/c32-24-8-3-20(4-9-24)22-7-14-27-23(17-22)19-38-34-29(27)31(37)33-28(18-35-15-1-2-16-35)30(36)21-5-10-25(11-6-21)39-26-12-13-26/h3-11,14,17,26,28,30,36H,1-2,12-13,15-16,18-19H2,(H,33,37)/t28-,30-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...				J Med Chem 51: 1319-23 (2008) BindingDB Entry DOI: 10.7270/Q2G44SK0
					More data for this Ligand-Target Pair