BDBM3677 4-N-(3-methylphenyl)-7-N-[3-(4-methylpiperazin-1-yl)propyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Methylphenyl)amino]-7-[[3-(4-methylpiperazin-1-yl)propyl]amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 4u

SMILES: CN1CCN(CCCNc2cc3ncnc(Nc4cccc(C)c4)c3cn2)CC1

InChI Key: InChIKey=ZSWVFFAVTCICJD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3677   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3677 (4-N-(3-methylphenyl)-7-N-[3-(4-methylpiperazin-1-y...) Show SMILES CN1CCN(CCCNc2cc3ncnc(Nc4cccc(C)c4)c3cn2)CC1 Show InChI InChI=1S/C22H29N7/c1-17-5-3-6-18(13-17)27-22-19-15-24-21(14-20(19)25-16-26-22)23-7-4-8-29-11-9-28(2)10-12-29/h3,5-6,13-16H,4,7-12H2,1-2H3,(H,23,24)(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 3915-25 (1997) Article DOI: 10.1021/jm970366v BindingDB Entry DOI: 10.7270/Q2NS0S2V
					More data for this Ligand-Target Pair