BDBM367845 3-(2-amino-7- methylbenzo[d]thiazol-4- yl)-6-(azetidin-3- ylsulfonyl)-2-(2H-tetrazol- 5-yl)benzenesulfonamide::US10227331, Example 32

SMILES: Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)C2CNC2)c2nc(N)sc12

InChI Key: InChIKey=FENLKZTUOZTGHO-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367845   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM367845 (3-(2-amino-7- methylbenzo[d]thiazol-4- yl)-6-(azet...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)C2CNC2)c2nc(N)sc12 Show InChI InChI=1S/C18H18N8O4S3/c1-8-2-3-11(14-15(8)31-18(19)22-14)10-4-5-12(32(27,28)9-6-21-7-9)16(33(20,29)30)13(10)17-23-25-26-24-17/h2-5,9,21H,6-7H2,1H3,(H2,19,22)(H2,20,29,30)(H,23,24,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.138	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
VIM-1 (Pseudomonas aeruginosa)	BDBM367845 (3-(2-amino-7- methylbenzo[d]thiazol-4- yl)-6-(azet...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)C2CNC2)c2nc(N)sc12 Show InChI InChI=1S/C18H18N8O4S3/c1-8-2-3-11(14-15(8)31-18(19)22-14)10-4-5-12(32(27,28)9-6-21-7-9)16(33(20,29)30)13(10)17-23-25-26-24-17/h2-5,9,21H,6-7H2,1H3,(H2,19,22)(H2,20,29,30)(H,23,24,25,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.106	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Beta-lactamase NDM-1 (Klebsiella pneumoniae)	BDBM367845 (3-(2-amino-7- methylbenzo[d]thiazol-4- yl)-6-(azet...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)C2CNC2)c2nc(N)sc12 Show InChI InChI=1S/C18H18N8O4S3/c1-8-2-3-11(14-15(8)31-18(19)22-14)10-4-5-12(32(27,28)9-6-21-7-9)16(33(20,29)30)13(10)17-23-25-26-24-17/h2-5,9,21H,6-7H2,1H3,(H2,19,22)(H2,20,29,30)(H,23,24,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0330	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair