BDBM367847 3-(2-amino-7- (trifluoromethyl)benzo[d] thiazol-4-yl)-6-(azetidin-3- ylsulfonyl)-2-(2H-tetrazol- 5-yl)benzenesulfonamide::US10227331, Example 34

SMILES: Nc1nc2c(ccc(c2s1)C(F)(F)F)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)C1CNC1

InChI Key: InChIKey=WWVBMIIORPYIMQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM367847 (3-(2-amino-7- (trifluoromethyl)benzo[d] thiazol-4-...) Show SMILES Nc1nc2c(ccc(c2s1)C(F)(F)F)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)C1CNC1 Show InChI InChI=1S/C18H15F3N8O4S3/c19-18(20,21)10-3-1-9(13-14(10)34-17(22)25-13)8-2-4-11(35(30,31)7-5-24-6-7)15(36(23,32)33)12(8)16-26-28-29-27-16/h1-4,7,24H,5-6H2,(H2,22,25)(H2,23,32,33)(H,26,27,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.229	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
VIM-1 (Pseudomonas aeruginosa)	BDBM367847 (3-(2-amino-7- (trifluoromethyl)benzo[d] thiazol-4-...) Show SMILES Nc1nc2c(ccc(c2s1)C(F)(F)F)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)C1CNC1 Show InChI InChI=1S/C18H15F3N8O4S3/c19-18(20,21)10-3-1-9(13-14(10)34-17(22)25-13)8-2-4-11(35(30,31)7-5-24-6-7)15(36(23,32)33)12(8)16-26-28-29-27-16/h1-4,7,24H,5-6H2,(H2,22,25)(H2,23,32,33)(H,26,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.175	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Beta-lactamase NDM-1 (Klebsiella pneumoniae)	BDBM367847 (3-(2-amino-7- (trifluoromethyl)benzo[d] thiazol-4-...) Show SMILES Nc1nc2c(ccc(c2s1)C(F)(F)F)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)C1CNC1 Show InChI InChI=1S/C18H15F3N8O4S3/c19-18(20,21)10-3-1-9(13-14(10)34-17(22)25-13)8-2-4-11(35(30,31)7-5-24-6-7)15(36(23,32)33)12(8)16-26-28-29-27-16/h1-4,7,24H,5-6H2,(H2,22,25)(H2,23,32,33)(H,26,27,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0710	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair