BDBM367852 2-amino-4-(4-(azetidin-3-ylsulfonyl)-3-sulfamoyl-2-(2H-tetrazol-5-yl)phenyl)benzo[d]thiazole-7-carboxamide::US10227331, Example 39

SMILES: NC(=O)c1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)C2CNC2)c2nc(N)sc12

InChI Key: InChIKey=PSYAIYVBWNAVRQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM367852 (2-amino-4-(4-(azetidin-3-ylsulfonyl)-3-sulfamoyl-2...) Show SMILES NC(=O)c1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)C2CNC2)c2nc(N)sc12 Show InChI InChI=1S/C18H17N9O5S3/c19-16(28)10-2-1-9(13-14(10)33-18(20)23-13)8-3-4-11(34(29,30)7-5-22-6-7)15(35(21,31)32)12(8)17-24-26-27-25-17/h1-4,7,22H,5-6H2,(H2,19,28)(H2,20,23)(H2,21,31,32)(H,24,25,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.276	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
VIM-1 protein (Pseudomonas aeruginosa)	BDBM367852 (2-amino-4-(4-(azetidin-3-ylsulfonyl)-3-sulfamoyl-2...) Show SMILES NC(=O)c1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)C2CNC2)c2nc(N)sc12 Show InChI InChI=1S/C18H17N9O5S3/c19-16(28)10-2-1-9(13-14(10)33-18(20)23-13)8-3-4-11(34(29,30)7-5-22-6-7)15(35(21,31)32)12(8)17-24-26-27-25-17/h1-4,7,22H,5-6H2,(H2,19,28)(H2,20,23)(H2,21,31,32)(H,24,25,26,27)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.129	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Klebsiella pneumoniae)	BDBM367852 (2-amino-4-(4-(azetidin-3-ylsulfonyl)-3-sulfamoyl-2...) Show SMILES NC(=O)c1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)C2CNC2)c2nc(N)sc12 Show InChI InChI=1S/C18H17N9O5S3/c19-16(28)10-2-1-9(13-14(10)33-18(20)23-13)8-3-4-11(34(29,30)7-5-22-6-7)15(35(21,31)32)12(8)17-24-26-27-25-17/h1-4,7,22H,5-6H2,(H2,19,28)(H2,20,23)(H2,21,31,32)(H,24,25,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair