BDBM368139 3-(2-aminobenzo[d]thiazol-4-yl)-6-((2-(dimethylamino)ethyl)sulfonyl)-2-(2H-tetrazol-5-yl)benzenesulfonamide::US10227331, Example 326

SMILES: CN(C)CCS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key: InChIKey=RIWPXELKJHELLJ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 368139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM368139 (3-(2-aminobenzo[d]thiazol-4-yl)-6-((2-(dimethylami...) Show SMILES CN(C)CCS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C18H20N8O4S3/c1-26(2)8-9-32(27,28)13-7-6-10(11-4-3-5-12-15(11)21-18(19)31-12)14(16(13)33(20,29)30)17-22-24-25-23-17/h3-7H,8-9H2,1-2H3,(H2,19,21)(H2,20,29,30)(H,22,23,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.248	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
VIM-1 (Pseudomonas aeruginosa)	BDBM368139 (3-(2-aminobenzo[d]thiazol-4-yl)-6-((2-(dimethylami...) Show SMILES CN(C)CCS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C18H20N8O4S3/c1-26(2)8-9-32(27,28)13-7-6-10(11-4-3-5-12-15(11)21-18(19)31-12)14(16(13)33(20,29)30)17-22-24-25-23-17/h3-7H,8-9H2,1-2H3,(H2,19,21)(H2,20,29,30)(H,22,23,24,25)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.167	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair
Beta-lactamase NDM-1 (Klebsiella pneumoniae)	BDBM368139 (3-(2-aminobenzo[d]thiazol-4-yl)-6-((2-(dimethylami...) Show SMILES CN(C)CCS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O Show InChI InChI=1S/C18H20N8O4S3/c1-26(2)8-9-32(27,28)13-7-6-10(11-4-3-5-12-15(11)21-18(19)31-12)14(16(13)33(20,29)30)17-22-24-25-23-17/h3-7H,8-9H2,1-2H3,(H2,19,21)(H2,20,29,30)(H,22,23,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0760	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				J Med Chem 51: 1231-41 (2008) BindingDB Entry DOI: 10.7270/Q2Z60RCD
					More data for this Ligand-Target Pair