null

SMILES: CNCCN(C)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1)C(F)(F)F

InChI Key: InChIKey=DCWUXXOCLXFRRQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM368308 (US10227338, Example 95) Show SMILES CNCCN(C)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1)C(F)(F)F Show InChI InChI=1S/C20H20ClF4N5O2S2/c1-26-5-6-30(2)17-7-12(20(23,24)25)3-4-15(17)28-16-9-14(22)18(8-13(16)21)34(31,32)29-19-10-33-11-27-19/h3-4,7-11,26,28-29H,5-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368308 (US10227338, Example 95) Show SMILES CNCCN(C)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1)C(F)(F)F Show InChI InChI=1S/C20H20ClF4N5O2S2/c1-26-5-6-30(2)17-7-12(20(23,24)25)3-4-15(17)28-16-9-14(22)18(8-13(16)21)34(31,32)29-19-10-33-11-27-19/h3-4,7-11,26,28-29H,5-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair