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SMILES: CNc1ncc2ncnc(Nc3cccc(C)c3)c2n1

InChI Key: InChIKey=CKGJCAISFNGPHH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3694 (2-N-methyl-8-N-(3-methylphenyl)-[1,3]diazino[5,4-d...) Show SMILES CNc1ncc2ncnc(Nc3cccc(C)c3)c2n1 Show InChI InChI=1S/C14H14N6/c1-9-4-3-5-10(6-9)19-13-12-11(17-8-18-13)7-16-14(15-2)20-12/h3-8H,1-2H3,(H,15,16,20)(H,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of EGFR				J Med Chem 51: 1179-88 (2008) Article DOI: 10.1021/jm070654j BindingDB Entry DOI: 10.7270/Q29Z95RD
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3694 (2-N-methyl-8-N-(3-methylphenyl)-[1,3]diazino[5,4-d...) Show SMILES CNc1ncc2ncnc(Nc3cccc(C)c3)c2n1 Show InChI InChI=1S/C14H14N6/c1-9-4-3-5-10(6-9)19-13-12-11(17-8-18-13)7-16-14(15-2)20-12/h3-8H,1-2H3,(H,15,16,20)(H,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	7.4	22
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 1820-6 (1997) Article DOI: 10.1021/jm960879m BindingDB Entry DOI: 10.7270/Q2J101C8
					More data for this Ligand-Target Pair