BDBM369810 US10233177, Example 89

SMILES: CC(C)(C)c1ccc(CNC(=O)Nc2cccc3NC(=O)COc23)cc1

InChI Key: InChIKey=NLLPAJAWVIAVHL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369810   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vanilloid receptor (Rattus norvegicus (rat))	BDBM369810 (US10233177, Example 89) Show SMILES CC(C)(C)c1ccc(CNC(=O)Nc2cccc3NC(=O)COc23)cc1 Show InChI InChI=1S/C20H23N3O3/c1-20(2,3)14-9-7-13(8-10-14)11-21-19(25)23-16-6-4-5-15-18(16)26-12-17(24)22-15/h4-10H,11-12H2,1-3H3,(H,22,24)(H2,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.8	n/a	n/a	n/a	n/a	n/a	n/a
Lund University					Assay Description Capsaicin (0.3 μM) caused an increase in [Ca2+] in the vast majority (95%) of dorsal root ganglia neurons, which were thereby identified as TRPV...				Bioorg Med Chem 14: 1215-20 (2006) BindingDB Entry DOI: 10.7270/Q20004DN
					More data for this Ligand-Target Pair