BindingDB logo
myBDB logout

null

SMILES: Cn1ncc(NC2CCCN(Cc3cc(Cl)cc(Cl)c3)C2)c(Cl)c1=O

InChI Key: InChIKey=HEUDMKLJRXWVDD-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371566   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371566
PNG
(4-chloro-5-((1-(3,5-dichlorobenzyl)piperidin-3-yl)...)
Show SMILES Cn1ncc(NC2CCCN(Cc3cc(Cl)cc(Cl)c3)C2)c(Cl)c1=O
Show InChI InChI=1S/C17H19Cl3N4O/c1-23-17(25)16(20)15(8-21-23)22-14-3-2-4-24(10-14)9-11-5-12(18)7-13(19)6-11/h5-8,14,22H,2-4,9-10H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 278n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair