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SMILES: Cn1cc(CN2CCCC(C2)Nc2cnn(C)c(=O)c2Cl)cn1

InChI Key: InChIKey=JWURCPZNTKHFLP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371571   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371571
PNG
(4-chloro-2-methyl-5-[[1-[(1-methylpyrazol-4-yl)met...)
Show SMILES Cn1cc(CN2CCCC(C2)Nc2cnn(C)c(=O)c2Cl)cn1
Show InChI InChI=1S/C15H21ClN6O/c1-20-8-11(6-17-20)9-22-5-3-4-12(10-22)19-13-7-18-21(2)15(23)14(13)16/h6-8,12,19H,3-5,9-10H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/a 371n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair