null

SMILES: FCCc1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1ccncn1)C(F)(F)F

InChI Key: InChIKey=ZOIWLLUKZWWVRB-GOSISDBHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM371729 (4-(2-(2-fluoroethyl)-4-(trifluoromethyl)phenyl)-N-...) Show SMILES FCCc1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1ccncn1)C(F)(F)F |r| Show InChI InChI=1S/C22H19F4N3O3S/c23-8-5-14-11-15(22(24,25)26)1-3-17(14)18-7-10-32-20-12-16(2-4-19(18)20)33(30,31)29-21-6-9-27-13-28-21/h1-4,6,9,11-13,18H,5,7-8,10H2,(H,27,28,29)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco					Assay Description HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...				J Med Chem 51: 545-52 (2008) BindingDB Entry DOI: 10.7270/Q2NG4SZX
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM371729 (4-(2-(2-fluoroethyl)-4-(trifluoromethyl)phenyl)-N-...) Show SMILES FCCc1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1ccncn1)C(F)(F)F |r| Show InChI InChI=1S/C22H19F4N3O3S/c23-8-5-14-11-15(22(24,25)26)1-3-17(14)18-7-10-32-20-12-16(2-4-19(18)20)33(30,31)29-21-6-9-27-13-28-21/h1-4,6,9,11-13,18H,5,7-8,10H2,(H,27,28,29)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco					Assay Description HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...				J Med Chem 51: 545-52 (2008) BindingDB Entry DOI: 10.7270/Q2NG4SZX
					More data for this Ligand-Target Pair