null
SMILES: CNC(=O)Cc1cccc(CNC(=O)CN2CN(c3ccccc3)C3(CCN(CC3)C(=O)c3ccc4[nH]ncc4c3)C2=O)c1
InChI Key: InChIKey=DEVDNVYDNDZDRO-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human)) | BDBM372067 (2-(3-((2-(8-(1H-indazole-5-carbonyl)-4-oxo-1-pheny...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 43.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri... | US Patent US10435407 (2019) BindingDB Entry DOI: 10.7270/Q2MP55M4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM372067 (2-(3-((2-(8-(1H-indazole-5-carbonyl)-4-oxo-1-pheny...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 43.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology | Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri... | J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB | |||||||||||
More data for this Ligand-Target Pair |