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SMILES: C[C@H](c1ccc(Cl)cc1Cl)n1nc(C)c2ncc(nc12)N1CCC(C(C)C1)N1CCC[C@H]1C1CC1C(O)=O

InChI Key: InChIKey=SHQNLOUAQUGYGA-FDCRACPRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374673   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM374673
PNG
(2-((2S)-1-(1-(1-((R)-1-(2,4-Dichlorophenyl)ethyl)-...)
Show SMILES C[C@H](c1ccc(Cl)cc1Cl)n1nc(C)c2ncc(nc12)N1CCC(C(C)C1)N1CCC[C@H]1C1CC1C(O)=O |r|
Show InChI InChI=1S/C28H34Cl2N6O2/c1-15-14-34(10-8-23(15)35-9-4-5-24(35)20-12-21(20)28(37)38)25-13-31-26-16(2)33-36(27(26)32-25)17(3)19-7-6-18(29)11-22(19)30/h6-7,11,13,15,17,20-21,23-24H,4-5,8-10,12,14H2,1-3H3,(H,37,38)/t15?,17-,20?,21?,23?,24+/m1/s1
UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a>500n/an/an/an/an/an/a



St. Jude Research Hospital



Assay Description
To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...

J Med Chem 50: 1876-85 (2007)


BindingDB Entry DOI: 10.7270/Q24F1T13
More data for this
Ligand-Target Pair