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SMILES: Fc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(cn2)-c2cccnn2)cc1F

InChI Key: InChIKey=DHTJGRRAHDTAOX-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 375017   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein Wnt-3a


(Homo sapiens (Human))		BDBM375017
PNG
(2-(3-fluoro-4-(2-fluoropyridin-4-yl)phenyl)-N-(5-(...)
Show SMILES Fc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(cn2)-c2cccnn2)cc1F
Show InChI InChI=1S/C22H15F2N5O/c23-18-10-14(3-5-17(18)15-7-9-25-20(24)12-15)11-22(30)28-21-6-4-16(13-26-21)19-2-1-8-27-29-19/h1-10,12-13H,11H2,(H,26,28,30)
PDB

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PC cid
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UniChem
US Patent
n/an/a 0.100n/an/an/an/an/an/a



St. Jude Research Hospital



Assay Description
Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...

J Med Chem 50: 5727-34 (2007)


BindingDB Entry DOI: 10.7270/Q2GM89KJ
More data for this
Ligand-Target Pair