null

SMILES: Nc1cc(Br)c(-c2ccnc(F)c2)c(n1)-c1ccncc1

InChI Key: InChIKey=GURBAXXWOCKMDW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 375233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2b (Homo sapiens (Human))	BDBM375233 (3-bromo-5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)p...) Show SMILES Nc1cc(Br)c(-c2ccnc(F)c2)c(n1)-c1ccncc1 Show InChI InChI=1S/C15H10BrFN4/c16-11-8-13(18)21-15(9-1-4-19-5-2-9)14(11)10-3-6-20-12(17)7-10/h1-8H,(H2,18,21)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine					Assay Description The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...				Proc Natl Acad Sci U S A 97: 925-30 (2000) BindingDB Entry DOI: 10.7270/Q2ZP48FV
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM375233 (3-bromo-5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)p...) Show SMILES Nc1cc(Br)c(-c2ccnc(F)c2)c(n1)-c1ccncc1 Show InChI InChI=1S/C15H10BrFN4/c16-11-8-13(18)21-15(9-1-4-19-5-2-9)14(11)10-3-6-20-12(17)7-10/h1-8H,(H2,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine					Assay Description The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...				Proc Natl Acad Sci U S A 97: 925-30 (2000) BindingDB Entry DOI: 10.7270/Q2ZP48FV
					More data for this Ligand-Target Pair