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SMILES: Cc1ccc(O)c(c1)C(=O)c1cc(C#N)c(=O)n(CC2CCCO2)c1

InChI Key: InChIKey=ZVTAYUCZPGRYDT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37553   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Huntingtin


(Homo sapiens (Human))		BDBM37553
PNG
(5-(2-hydroxy-5-methyl-benzoyl)-2-keto-1-(tetrahydr...)
Show SMILES Cc1ccc(O)c(c1)C(=O)c1cc(C#N)c(=O)n(CC2CCCO2)c1
Show InChI InChI=1S/C19H18N2O4/c1-12-4-5-17(22)16(7-12)18(23)14-8-13(9-20)19(24)21(10-14)11-15-3-2-6-25-15/h4-5,7-8,10,15,22H,2-3,6,11H2,1H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
PCBioAssay
n/an/a>8.00E+3n/an/an/an/an/an/a



Columbia University Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...

PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2SQ8XSH
More data for this
Ligand-Target Pair