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SMILES: CCN(CC)CCn1c2ccc(OC)cc2c2c(Nc3cccc(Br)c3)ncnc12

InChI Key: InChIKey=KGOOHLRXQJDOJF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3759   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM3759
PNG
(N-(3-bromophenyl)-9-[2-(diethylamino)ethyl]-6-meth...)
Show SMILES CCN(CC)CCn1c2ccc(OC)cc2c2c(Nc3cccc(Br)c3)ncnc12
Show InChI InChI=1S/C23H26BrN5O/c1-4-28(5-2)11-12-29-20-10-9-18(30-3)14-19(20)21-22(25-15-26-23(21)29)27-17-8-6-7-16(24)13-17/h6-10,13-15H,4-5,11-12H2,1-3H3,(H,25,26,27)
PDB
MMDB

KEGG

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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 4.27E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...

J Med Chem 42: 5464-74 (1999)


Article DOI: 10.1021/jm9903949
BindingDB Entry DOI: 10.7270/Q28K7783
More data for this
Ligand-Target Pair