BDBM376019 N-(3-methyl-1-phenyl-1H- 1,2,4-triazol-5-yl)-3-(1- methyl-1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 15

SMILES: Cc1nc(NC(=O)c2ccc(c(c2)-c2ccn(C)n2)C(F)(F)F)n(n1)-c1ccccc1

InChI Key: InChIKey=KWKAXGKSMXIBEV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM376019 (N-(3-methyl-1-phenyl-1H- 1,2,4-triazol-5-yl)-3-(1-...) Show SMILES Cc1nc(NC(=O)c2ccc(c(c2)-c2ccn(C)n2)C(F)(F)F)n(n1)-c1ccccc1 Show InChI InChI=1S/C21H17F3N6O/c1-13-25-20(30(27-13)15-6-4-3-5-7-15)26-19(31)14-8-9-17(21(22,23)24)16(12-14)18-10-11-29(2)28-18/h3-12H,1-2H3,(H,25,26,27,31)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur					Assay Description In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...				J Med Chem 51: 3077-80 (2008) BindingDB Entry DOI: 10.7270/Q2WQ0629
					More data for this Ligand-Target Pair