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SMILES: CN(C)CCOCCn1cnc(c1)-c1cc(ccn1)C(O)=O

InChI Key: InChIKey=CGBVLABAVLQTCP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 381989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM381989 (2-(1-{2-[2- (dimethylamino)ethoxy]ethyl}- 1H-imida...) Show SMILES CN(C)CCOCCn1cnc(c1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C15H20N4O3/c1-18(2)5-7-22-8-6-19-10-14(17-11-19)13-9-12(15(20)21)3-4-16-13/h3-4,9-11H,5-8H2,1-2H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...				J Med Chem 51: 5502-5 (2008) BindingDB Entry DOI: 10.7270/Q2DF6THR
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM381989 (2-(1-{2-[2- (dimethylamino)ethoxy]ethyl}- 1H-imida...) Show SMILES CN(C)CCOCCn1cnc(c1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C15H20N4O3/c1-18(2)5-7-22-8-6-19-10-14(17-11-19)13-9-12(15(20)21)3-4-16-13/h3-4,9-11H,5-8H2,1-2H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				J Med Chem 51: 5502-5 (2008) BindingDB Entry DOI: 10.7270/Q2DF6THR
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM381989 (2-(1-{2-[2- (dimethylamino)ethoxy]ethyl}- 1H-imida...) Show SMILES CN(C)CCOCCn1cnc(c1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C15H20N4O3/c1-18(2)5-7-22-8-6-19-10-14(17-11-19)13-9-12(15(20)21)3-4-16-13/h3-4,9-11H,5-8H2,1-2H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				J Med Chem 51: 5502-5 (2008) BindingDB Entry DOI: 10.7270/Q2DF6THR
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4A (Homo sapiens (Human))	BDBM381989 (2-(1-{2-[2- (dimethylamino)ethoxy]ethyl}- 1H-imida...) Show SMILES CN(C)CCOCCn1cnc(c1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C15H20N4O3/c1-18(2)5-7-22-8-6-19-10-14(17-11-19)13-9-12(15(20)21)3-4-16-13/h3-4,9-11H,5-8H2,1-2H3,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...				J Med Chem 51: 5502-5 (2008) BindingDB Entry DOI: 10.7270/Q2DF6THR
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM381989 (2-(1-{2-[2- (dimethylamino)ethoxy]ethyl}- 1H-imida...) Show SMILES CN(C)CCOCCn1cnc(c1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C15H20N4O3/c1-18(2)5-7-22-8-6-19-10-14(17-11-19)13-9-12(15(20)21)3-4-16-13/h3-4,9-11H,5-8H2,1-2H3,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				J Med Chem 51: 5502-5 (2008) BindingDB Entry DOI: 10.7270/Q2DF6THR
					More data for this Ligand-Target Pair