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BDBM382128 4-(4-((4'-methoxy-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methoxy) phenyl)butanoic Acid::US10273230, Compound of Example 6

SMILES: COc1ccc(cc1)C1=C(COc2ccc(CCCC(O)=O)cc2)CCCC1

InChI Key: InChIKey=WFXBWJBCUISEEL-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 382128   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Free fatty acid receptor 4


(Homo sapiens (Human))		BDBM382128
PNG
(4-(4-((4'-methoxy-3,4,5,6-tetrahydro-[1,1'-bipheny...)
Show SMILES COc1ccc(cc1)C1=C(COc2ccc(CCCC(O)=O)cc2)CCCC1 |c:9|
Show InChI InChI=1S/C24H28O4/c1-27-21-15-11-19(12-16-21)23-7-3-2-6-20(23)17-28-22-13-9-18(10-14-22)5-4-8-24(25)26/h9-16H,2-8,17H2,1H3,(H,25,26)
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.75E+3n/an/an/an/a



IRBM/Merck



Assay Description
Beta (β) arrestin 2 Interaction Assay (BRET assay) was performed using CHO-K1 cells stably expressing the GPR120 receptor using β-galactosi...

Bioorg Med Chem Lett 18: 3456-61 (2008)


BindingDB Entry DOI: 10.7270/Q2154KBP
More data for this
Ligand-Target Pair