BDBM382806 US10273259, Example 517::US10711020, Example 517

SMILES: Fc1cccc(c1)S(=O)(=O)C12CCN(C1CNc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)C(=O)C1CCS(=O)(=O)CC1

InChI Key: InChIKey=SRKHSAMWTXLEMM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 382806   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM382806 (US10273259, Example 517 | US10711020, Example 517) Show SMILES Fc1cccc(c1)S(=O)(=O)C12CCN(C1CNc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)C(=O)C1CCS(=O)(=O)CC1 Show InChI InChI=1S/C26H24F8N2O5S2/c27-17-2-1-3-18(13-17)43(40,41)23-8-9-36(22(37)15-6-10-42(38,39)11-7-15)21(23)14-35-20-12-16(4-5-19(20)23)24(28,25(29,30)31)26(32,33)34/h1-5,12-13,15,21,35H,6-11,14H2	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...				US Patent US10711020 (2020)
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Mus musculus)	BDBM382806 (US10273259, Example 517 | US10711020, Example 517) Show SMILES Fc1cccc(c1)S(=O)(=O)C12CCN(C1CNc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)C(=O)C1CCS(=O)(=O)CC1 Show InChI InChI=1S/C26H24F8N2O5S2/c27-17-2-1-3-18(13-17)43(40,41)23-8-9-36(22(37)15-6-10-42(38,39)11-7-15)21(23)14-35-20-12-16(4-5-19(20)23)24(28,25(29,30)31)26(32,33)34/h1-5,12-13,15,21,35H,6-11,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2MW2KG7
					More data for this Ligand-Target Pair