BDBM383972 US10280166, Compound 82

SMILES: c1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccnc3)c2c1

InChI Key: InChIKey=SDNDONPGVQMPDO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM383972 (US10280166, Compound 82) Show SMILES c1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccnc3)c2c1 Show InChI InChI=1S/C23H15N7/c1-3-15(12-24-8-1)14-5-6-19-18(11-14)21(30-29-19)23-27-20-17(7-10-26-22(20)28-23)16-4-2-9-25-13-16/h1-13H,(H,29,30)(H,26,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham					Assay Description Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...				Br J Pharmacol 144: 317-22 (2005) BindingDB Entry DOI: 10.7270/Q22Z17VC
					More data for this Ligand-Target Pair