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SMILES: Nc1nc(nc2n(Cc3ccccc3)c(=O)[nH]c12)-c1ccco1

InChI Key: InChIKey=HBVYNNJLQGRITE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384093   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM384093
PNG
(US10280167, Example 20)
Show SMILES Nc1nc(nc2n(Cc3ccccc3)c(=O)[nH]c12)-c1ccco1
Show InChI InChI=1S/C16H13N5O2/c17-13-12-15(20-14(19-13)11-7-4-8-23-11)21(16(22)18-12)9-10-5-2-1-3-6-10/h1-8H,9H2,(H,18,22)(H2,17,19,20)
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 680n/an/an/an/a



University of Nottingham



Assay Description
Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...

Br J Pharmacol 144: 317-22 (2005)


BindingDB Entry DOI: 10.7270/Q2Z60RDV
More data for this
Ligand-Target Pair