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SMILES: Nc1nc(nc2n(Cc3ccccc3)c(=O)[nH]c12)-c1ccn[nH]1

InChI Key: InChIKey=ORGQRQQMJQETEM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384094   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM384094
PNG
(US10280167, Example 23)
Show SMILES Nc1nc(nc2n(Cc3ccccc3)c(=O)[nH]c12)-c1ccn[nH]1
Show InChI InChI=1S/C15H13N7O/c16-12-11-14(20-13(19-12)10-6-7-17-21-10)22(15(23)18-11)8-9-4-2-1-3-5-9/h1-7H,8H2,(H,17,21)(H,18,23)(H2,16,19,20)
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 130n/an/an/an/a



University of Nottingham



Assay Description
Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...

Br J Pharmacol 144: 317-22 (2005)


BindingDB Entry DOI: 10.7270/Q2Z60RDV
More data for this
Ligand-Target Pair