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SMILES: CCc1c[nH]c(n1)-c1nc(N)c2[nH]c(=O)n(Cc3ccccc3)c2n1

InChI Key: InChIKey=WSLFACHRRYNYSN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384101   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM384101
PNG
(US10280167, Example 30)
Show SMILES CCc1c[nH]c(n1)-c1nc(N)c2[nH]c(=O)n(Cc3ccccc3)c2n1
Show InChI InChI=1S/C17H17N7O/c1-2-11-8-19-14(20-11)15-22-13(18)12-16(23-15)24(17(25)21-12)9-10-6-4-3-5-7-10/h3-8H,2,9H2,1H3,(H,19,20)(H,21,25)(H2,18,22,23)
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 170n/an/an/an/a



University of Nottingham



Assay Description
Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...

Br J Pharmacol 144: 317-22 (2005)


BindingDB Entry DOI: 10.7270/Q2Z60RDV
More data for this
Ligand-Target Pair