BDBM384105 US10280167, Example 34

SMILES: COCCc1nnc(o1)-c1nc(N)c2[nH]c(=O)n(Cc3ccccc3)c2n1

InChI Key: InChIKey=CDHVTQXUHOQZDN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM384105 (US10280167, Example 34) Show SMILES COCCc1nnc(o1)-c1nc(N)c2[nH]c(=O)n(Cc3ccccc3)c2n1 Show InChI InChI=1S/C17H17N7O3/c1-26-8-7-11-22-23-16(27-11)14-20-13(18)12-15(21-14)24(17(25)19-12)9-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3,(H,19,25)(H2,18,20,21)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
University of Nottingham					Assay Description Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...				Br J Pharmacol 144: 317-22 (2005) BindingDB Entry DOI: 10.7270/Q2Z60RDV
					More data for this Ligand-Target Pair