null

SMILES: CCNc1nc(Nc2cn(nc2C2CC2)S(C)(=O)=O)ncc1C(F)(F)F

InChI Key: InChIKey=OALFONBONKOVKV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 384426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384426 (US10590114, No. 112 | US11111235, No. 112 | US9932...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)S(C)(=O)=O)ncc1C(F)(F)F Show InChI InChI=1S/C14H17F3N6O2S/c1-3-18-12-9(14(15,16)17)6-19-13(21-12)20-10-7-23(26(2,24)25)22-11(10)8-4-5-8/h6-8H,3-5H2,1-2H3,(H2,18,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				Bioorg Med Chem Lett 18: 2567-73 (2008) BindingDB Entry DOI: 10.7270/Q29G5Q4M
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM384426 (US10590114, No. 112 | US11111235, No. 112 | US9932...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)S(C)(=O)=O)ncc1C(F)(F)F Show InChI InChI=1S/C14H17F3N6O2S/c1-3-18-12-9(14(15,16)17)6-19-13(21-12)20-10-7-23(26(2,24)25)22-11(10)8-4-5-8/h6-8H,3-5H2,1-2H3,(H2,18,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384426 (US10590114, No. 112 | US11111235, No. 112 | US9932...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)S(C)(=O)=O)ncc1C(F)(F)F Show InChI InChI=1S/C14H17F3N6O2S/c1-3-18-12-9(14(15,16)17)6-19-13(21-12)20-10-7-23(26(2,24)25)22-11(10)8-4-5-8/h6-8H,3-5H2,1-2H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020)
					More data for this Ligand-Target Pair