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SMILES: Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)C2CC2)c1

InChI Key: InChIKey=LOQYMTXWNTWVBJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384555   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384555
PNG
(US10285982, Compound 20)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)C2CC2)c1
Show InChI InChI=1S/C28H20FN7O/c29-18-3-1-2-16(8-18)20-6-7-31-27-21(20)10-24(34-27)26-22-11-23(32-14-25(22)35-36-26)17-9-19(13-30-12-17)33-28(37)15-4-5-15/h1-3,6-15H,4-5H2,(H,31,34)(H,33,37)(H,35,36)
UniProtKB/SwissProt

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UniChem
US Patent
n/an/an/an/a 97n/an/an/an/a



Istanbul University



Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2J105G8
More data for this
Ligand-Target Pair