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SMILES: FC1(F)CCN(Cc2cncc(c2)-c2cc3c(n[nH]c3cn2)-c2cc3cccnc3[nH]2)C1

InChI Key: InChIKey=UZTQLBFRFIMMPV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384701   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384701
PNG
(US10285982, Compound 278)
Show SMILES FC1(F)CCN(Cc2cncc(c2)-c2cc3c(n[nH]c3cn2)-c2cc3cccnc3[nH]2)C1
Show InChI InChI=1S/C23H19F2N7/c24-23(25)3-5-32(13-23)12-14-6-16(10-26-9-14)18-8-17-20(11-28-18)30-31-21(17)19-7-15-2-1-4-27-22(15)29-19/h1-2,4,6-11H,3,5,12-13H2,(H,27,29)(H,30,31)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.35E+3n/an/an/an/a



Istanbul University



Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2J105G8
More data for this
Ligand-Target Pair