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BDBM384783 US10285983, Compound 601

SMILES: C1CCN(CC1)c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)C1CCNCC1

InChI Key: InChIKey=WAULOKQIIMWWPX-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384783   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384783
PNG
(US10285983, Compound 601)
Show SMILES C1CCN(CC1)c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)C1CCNCC1
Show InChI InChI=1S/C23H27N7/c1-2-10-30(11-3-1)20-6-9-25-22-17(20)13-19(27-22)21-18-12-16(14-26-23(18)29-28-21)15-4-7-24-8-5-15/h6,9,12-15,24H,1-5,7-8,10-11H2,(H,25,27)(H,26,28,29)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair