BDBM385076 US10287258, Example 36

SMILES: CC[C@H](NC(=O)[C@@H]1CNCCCO1)\C=C\C(=O)N1CCc2ccccc12

InChI Key: InChIKey=OHNHQTNQBQMALV-LFGVRAQPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM385076 (US10287258, Example 36) Show SMILES CC[C@H](NC(=O)[C@@H]1CNCCCO1)\C=C\C(=O)N1CCc2ccccc12 |r| Show InChI InChI=1S/C20H27N3O3/c1-2-16(22-20(25)18-14-21-11-5-13-26-18)8-9-19(24)23-12-10-15-6-3-4-7-17(15)23/h3-4,6-9,16,18,21H,2,5,10-14H2,1H3,(H,22,25)/b9-8+/t16-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...				J Med Chem 51: 7049-52 (2008) BindingDB Entry DOI: 10.7270/Q2RJ4MTP
					More data for this Ligand-Target Pair