BDBM385700 4-{7-[(2,2- difluoroethyl) amino]- [1,2,4]triazolo[1,5- a]pyridin-5- yl}benzonitrile::US10287286, Example 106

SMILES: FC(F)CNc1cc(-c2ccc(cc2)C#N)n2ncnc2c1

InChI Key: InChIKey=RVSQXEPIPJUJSE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 2 (Homo sapiens (Human))	BDBM385700 (4-{7-[(2,2- difluoroethyl) amino]- [1,2,4]triazolo...) Show SMILES FC(F)CNc1cc(-c2ccc(cc2)C#N)n2ncnc2c1 Show InChI InChI=1S/C15H11F2N5/c16-14(17)8-19-12-5-13(22-15(6-12)20-9-21-22)11-3-1-10(7-18)2-4-11/h1-6,9,14,19H,8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...				Bioorg Med Chem 16: 7424-8 (2008) BindingDB Entry DOI: 10.7270/Q2QJ7KMD
					More data for this Ligand-Target Pair