BDBM385850 US10287286, Example 248

SMILES: Cc1cc(ncc1-c1cc(N)cc2ncnn12)C#N

InChI Key: InChIKey=XMKSYWRTYPXQRC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 2 (Homo sapiens (Human))	BDBM385850 (US10287286, Example 248) Show SMILES Cc1cc(ncc1-c1cc(N)cc2ncnn12)C#N Show InChI InChI=1S/C13H10N6/c1-8-2-10(5-14)16-6-11(8)12-3-9(15)4-13-17-7-18-19(12)13/h2-4,6-7H,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...				Bioorg Med Chem 16: 7424-8 (2008) BindingDB Entry DOI: 10.7270/Q2QJ7KMD
					More data for this Ligand-Target Pair