null

SMILES: CCCNC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@H](CC1)C(C)C

InChI Key: InChIKey=FKLCVQLKHNAGTR-RDGPPVDQSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 386147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM386147 (US10287305, Example 100 | US10508083, Example 100 ...) Show SMILES CCCNC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@H](CC1)C(C)C |r,wU:22.26,19.19,16.17,10.10,(-4.67,-3.85,;-3.33,-3.08,;-2,-3.85,;-.67,-3.08,;.67,-3.85,;.67,-5.39,;2,-3.08,;3.33,-3.85,;4.67,-3.08,;4.67,-1.54,;3.33,-.77,;3.33,.77,;4.67,1.54,;6,.77,;3.9,2.87,;5.44,2.87,;2,-1.54,;.67,-.77,;.67,.77,;-.67,1.54,;-2,.77,;-3.33,1.54,;-3.33,3.08,;-2,3.85,;-.67,3.08,;-4.67,3.85,;-6,3.08,;-4.67,5.39,)| Show InChI InChI=1S/C20H39N3O4S/c1-5-12-21-20(24)23-13-6-7-18(22-28(4,25)26)19(23)14-27-17-10-8-16(9-11-17)15(2)3/h15-19,22H,5-14H2,1-4H3,(H,21,24)/t16-,17+,18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...				J Med Chem 50: 2213-24 (2007) BindingDB Entry DOI: 10.7270/Q2Z321Z2
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM386147 (US10287305, Example 100 | US10508083, Example 100 ...) Show SMILES CCCNC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@H](CC1)C(C)C |r,wU:22.26,19.19,16.17,10.10,(-4.67,-3.85,;-3.33,-3.08,;-2,-3.85,;-.67,-3.08,;.67,-3.85,;.67,-5.39,;2,-3.08,;3.33,-3.85,;4.67,-3.08,;4.67,-1.54,;3.33,-.77,;3.33,.77,;4.67,1.54,;6,.77,;3.9,2.87,;5.44,2.87,;2,-1.54,;.67,-.77,;.67,.77,;-.67,1.54,;-2,.77,;-3.33,1.54,;-3.33,3.08,;-2,3.85,;-.67,3.08,;-4.67,3.85,;-6,3.08,;-4.67,5.39,)| Show InChI InChI=1S/C20H39N3O4S/c1-5-12-21-20(24)23-13-6-7-18(22-28(4,25)26)19(23)14-27-17-10-8-16(9-11-17)15(2)3/h15-19,22H,5-14H2,1-4H3,(H,21,24)/t16-,17+,18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM386147 (US10287305, Example 100 | US10508083, Example 100 ...) Show SMILES CCCNC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@H](CC1)C(C)C |r,wU:22.26,19.19,16.17,10.10,(-4.67,-3.85,;-3.33,-3.08,;-2,-3.85,;-.67,-3.08,;.67,-3.85,;.67,-5.39,;2,-3.08,;3.33,-3.85,;4.67,-3.08,;4.67,-1.54,;3.33,-.77,;3.33,.77,;4.67,1.54,;6,.77,;3.9,2.87,;5.44,2.87,;2,-1.54,;.67,-.77,;.67,.77,;-.67,1.54,;-2,.77,;-3.33,1.54,;-3.33,3.08,;-2,3.85,;-.67,3.08,;-4.67,3.85,;-6,3.08,;-4.67,5.39,)| Show InChI InChI=1S/C20H39N3O4S/c1-5-12-21-20(24)23-13-6-7-18(22-28(4,25)26)19(23)14-27-17-10-8-16(9-11-17)15(2)3/h15-19,22H,5-14H2,1-4H3,(H,21,24)/t16-,17+,18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...				US Patent US10508083 (2019) BindingDB Entry DOI: 10.7270/Q29S1TD1
					More data for this Ligand-Target Pair