BDBM38943 2-(1,3-benzothiazol-2-yl)-1-phthalazinone::2-(1,3-benzothiazol-2-yl)phthalazin-1-one::MLS000055243::SMR000065646::cid_727725
SMILES: O=c1n(ncc2ccccc12)-c1nc2ccccc2s1
InChI Key: InChIKey=XAVNIJZYVBDIPG-UHFFFAOYSA-N
Data: 9 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nuclear receptor ROR-alpha (Alpha-2) (Homo sapiens (Human)) | BDBM38943 (2-(1,3-benzothiazol-2-yl)-1-phthalazinone | 2-(1,3...) | PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 847 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2TH8K3N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM38943 (2-(1,3-benzothiazol-2-yl)-1-phthalazinone | 2-(1,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 728 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2PR7TCX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-alpha (Alpha-2) (Homo sapiens (Human)) | BDBM38943 (2-(1,3-benzothiazol-2-yl)-1-phthalazinone | 2-(1,3...) | PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 2.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q26Q1VNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM38943 (2-(1,3-benzothiazol-2-yl)-1-phthalazinone | 2-(1,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 2.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2319T8T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Luciferin 4-monooxygenase (Photinus pyralis) | BDBM38943 (2-(1,3-benzothiazol-2-yl)-1-phthalazinone | 2-(1,3...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute Curated by ChEMBL | Assay Description Inhibition of Photinus pyralis luciferase | J Med Chem 51: 2372-86 (2008) Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Luciferin 4-monooxygenase (Photinus pyralis) | BDBM38943 (2-(1,3-benzothiazol-2-yl)-1-phthalazinone | 2-(1,3...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute Curated by ChEMBL | Assay Description Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assay | J Med Chem 51: 2372-86 (2008) Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Luciferin 4-monooxygenase (Photinus pyralis) | BDBM38943 (2-(1,3-benzothiazol-2-yl)-1-phthalazinone | 2-(1,3...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute Curated by ChEMBL | Assay Description Inhibition of Photinus pyralis luciferase by PK-Light assay | J Med Chem 51: 2372-86 (2008) Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Luciferin 4-monooxygenase (Photinus pyralis) | BDBM38943 (2-(1,3-benzothiazol-2-yl)-1-phthalazinone | 2-(1,3...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute Curated by ChEMBL | Assay Description Inhibition of Photinus pyralis luciferase by Easy lite assay | J Med Chem 51: 2372-86 (2008) Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Luciferin 4-monooxygenase (Photinus pyralis) | BDBM38943 (2-(1,3-benzothiazol-2-yl)-1-phthalazinone | 2-(1,3...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
National Human Genome Research Institute Curated by ChEMBL | Assay Description Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assay | J Med Chem 51: 2372-86 (2008) Article DOI: 10.1021/jm701302v BindingDB Entry DOI: 10.7270/Q2F192HZ | |||||||||||
More data for this Ligand-Target Pair |